Zedman® (Tapinarof Cream)
Twice daily (morning and evening), steroid-free topical treatment. Indicated for patients aged 2 years and older.
In Clinical Studies, Zedman® Demonstrated:
Marked Improvement in Skin Lesions

EASI75 (Week 8): 54.4% vs 25.5% (~~P<0.001~~ P < 0.001)

IGA 0/1 at Week 8: Zedman® 46.2% vs Placebo 21.4% (P<0.001)²

EASI90 (Week 8): 33.9% vs 13.5% (P<0.001)

Pruritus Relief

PP-NRS Reduction ≥3 Points (Week 8): Zedman® 54.0% vs Placebo 27.9%

Good Safety and Tolerability*

Adverse reactions were mild to moderate and transient.

IGA: Investigator's Global Assessment; EASI: Eczema Area and Severity Index;
PP-NRS: Peak Pruritus Numerical Rating Scale. *Data source: Tapinarof 1% Cream Phase III Randomized Controlled Study²
Learn About the Mechanism of Action
Important Safety Information
Indication: Zedman® (Tapinarof Cream, concentration/strength per package insert)is a drug with an aryl hydrocarbon receptor (AhR)-related mechanism of action. It is indicated for the topical treatment of patients aged 2 years and older.
*Observed adverse events (% placebo-adjusted): application site reactions (7.6%), folliculitis (3.2%), contact dermatitis (0.4%), headache (1.6%).